What are you meaning? To make the explosion look like its made of voxels or something else?
You can use cube primitives to make a “voxel-like” explosion in 3D with a Particles node. From there, its just a matter of changing the particles process material until you get a result you like.
For making a voxel crater where the explosion is, similar to the effect TNT leaves in Minecraft, you just need to get all of the voxels around the origin of the explosion in a sphere like pattern. I have not done such a thing myself, but I’m sure there is example code on the internet for getting points on a sphere with a given radius. Somethings like the code example (plus the answer) in this StackOverflow answer. Just instead of getting a single point, you want to get multiple. Then you get the nearest voxel from each of those points on the sphere, and that should (in theory) give you a spherical explosion.