I'll repeat here what I wrote in the PM as well.
That toggle only controls the viewport gizmo. I suggested toggling it to see a preview of whats going on with your object in local space. Inspector still works exactly the same though.
For your solution, using one of the enemy balls from your game you posted for me:
Create 2 AnimationPlayers for your Enemy1 node:

AnimationPlayer will contain multiple animations, each individual one will be rolling in a specific direction. Say one animation fro rolling towards north, another for east, then one for rolling west, then finally one for rolling south.
The other AnimationPlayer I have renamed AnimationController will have a Animation Playback track in it, which will control the other animation player and tell it which animation to play and when. To add a animation playback track, with the AnimationController node selected in the animation editor press + Add track
:

Once you have done that in the top right corner of the animation editor you will find a pin icon, press it so the animation player wont switch to show the contents of the other animation player, and select the animation player containing the individual animations for the different rolling directions.
Now in inspector you will see the property for current animation, this is what you will be keying over time so as to switch between the different animations:


This way you don't have to deal with the issue at all. :)